Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Deborah Muoio
PROVIDER: PXD030674 | JPOST Repository | Thu Dec 30 00:00:00 GMT 2021
REPOSITORIES: jPOST
Items per page: 5 1 - 5 of 20 |
Wilson Rebecca J RJ Lyons Scott P SP Koves Timothy R TR Bryson Victoria G VG Zhang Hengtao H Li TianYu T Crown Scott B SB Ding Jin-Dong JD Grimsrud Paul A PA Rosenberg Paul B PB Muoio Deborah M DM
Molecular metabolism 20211231
<h4>Objective</h4>Stromal interaction molecule 1 (STIM1) is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in a store operated Ca<sup>2+</sup> entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STIM1 is known to be indispensable during development, its biological and metabolic functions in mature muscles remain unclear.<h4>Methods</h4>Conditional and tamoxifen inducible muscle STIM1 knock-out mouse models were coupled with mu ...[more]