Dataset Information
Proteomic study of the mice treated with antibiotics
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Sumio Ohtsuki
PROVIDER: PXD037296 | JPOST Repository | Wed Jul 12 00:00:00 BST 2023
REPOSITORIES: jPOST
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Liver%20CM_Anti-1.wiff | Wiff | |||
| Liver%20CM_Anti-1.wiff.scan | Wiff | |||
| Liver%20CM_Anti-2.wiff | Wiff | |||
| Liver%20CM_Anti-2.wiff.scan | Wiff | |||
| Liver%20CM_Anti-3.wiff | Wiff |
Items per page: 1 - 5 of 20 |
Publications
Effect of antibiotic-administration period on hepatic bile acid profile and expression of pharmacokinetic-related proteins in mouse liver, kidney, and brain capillaries.
Drug metabolism and pharmacokinetics 20230209
Antibiotic administration affects pharmacokinetics through changes in the intestinal microbiota, and bile acids are involved in this regulation. The purpose of the present study was to clarify the effect of different periods of antibiotic administration on the hepatic bile acid profile and expression of pharmacokinetic-related proteins in mouse liver, kidney, and brain capillaries. Vancomycin and polymyxin B were orally administered to mice for either 5- or 25-days. The hepatic bile acid profile ...[more]