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Opisthorchis viverrini infection exacerbates kidney disease through gut dysbiosis and alteration of host proteome in nonalcoholic steatohepatitis hamsters

ABSTRACT: Non–alcoholic fatty liver disease (NAFLD) is high prevalent in worldwide and associated with chronic kidney disease (CKD). Infection with Opisthorchis viverrini (Ov) infection and consumption of high fat and high fructose (HFF) exacerbates NAFLD to nonalcoholic steatohepatitis in hamsters. Here, we aimed to investigate the effect a combination of HFF diet and Ov infection on kidney pathology via alteration of gut microbiome and proteome in hamster.

ORGANISM(S): Cellular Organisms

SUBMITTER: Somchai Pinlaor

PROVIDER: PXD045309 | JPOST Repository | Thu Sep 12 00:00:00 BST 2024

REPOSITORIES: jPOST

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