Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Deborah M. Muoio
PROVIDER: PXD047114 | JPOST Repository | Fri Feb 09 00:00:00 GMT 2024
REPOSITORIES: jPOST
Items per page: 5 1 - 5 of 20 |
Williams Ashley S AS Crown Scott B SB Lyons Scott P SP Koves Timothy R TR Wilson Rebecca J RJ Johnson Jordan M JM Slentz Dorothy H DH Kelly Daniel P DP Grimsrud Paul A PA Zhang Guo-Fang GF Muoio Deborah M DM
Cell metabolism 20240201 2
Time-restricted feeding (TRF) has gained attention as a dietary regimen that promotes metabolic health. This study questioned if the health benefits of an intermittent TRF (iTRF) schedule require ketone flux specifically in skeletal and cardiac muscles. Notably, we found that the ketolytic enzyme beta-hydroxybutyrate dehydrogenase 1 (BDH1) is uniquely enriched in isolated mitochondria derived from heart and red/oxidative skeletal muscles, which also have high capacity for fatty acid oxidation (F ...[more]