Proteomics

Dataset Information

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Quantitative Proteomic Analysis of Residual Host Cell Protein Retention Across Adeno- Associated Virus (AAV) Affinity Chromatography


ABSTRACT: To better understand host cell protein (HCP) retention in adeno-associated virus (AAV) downstream processes, sequential windowed acquisition of all theoretical fragment ion mass spectra (SWATH-MS) was used to quantitatively profile residual HCPs for four AAV serotypes (2, 5, 8, and 9) produced with HEK293 cells and purified using POROS™ CaptureSelect™ AAVX affinity chromatography.

ORGANISM(S): Cellular Organisms

SUBMITTER: Kelvin H. Lee 

PROVIDER: PXD056294 | JPOST Repository | Thu Dec 12 00:00:00 GMT 2024

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
AAV2_B1.zip Other
AAV2_B2.zip Other
AAV5_B1.zip Other
AAV5_B2.zip Other
AAV8_B1.zip Other
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