Dataset Information

Proteomic analysis of lung tissues in an oleic acid (OA)-induced acute lung injury model rats

ABSTRACT: Data analyzed proteins extracted from lung tissue samples from OA-induced acute lung injury model rats. Samples were collected at 0 (pretreatment), 3, 6, 24, 48, 96 h after OA administration. Whole tissue extracts were prepared from three individuals and analyzed using the DIA-MS method.

ORGANISM(S): Cellular Organisms

SUBMITTER: Noriaki Arakawa

PROVIDER: PXD057386 | JPOST Repository | Fri Mar 14 00:00:00 GMT 2025

REPOSITORIES: jPOST

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Dataset's files

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			Action	DRS
	0h_1.mzML	Mzml
	0h_2.mzML	Mzml
	20240426_Yoshida_R45000_P700_0h_1.raw	Raw
	20240426_Yoshida_R45000_P700_0h_2.raw	Raw
	20240426_Yoshida_R45000_P700_0h_3.raw	Raw

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Publications

Analysis of Stratifin Expression and Proteome Variation in a Rat Model of Acute Lung Injury.

Yoshida Ayaka A Hashimoto Yuya Y Akane Hirotoshi H Matsuyama Shinichiro S Toyoda Takeshi T Ogawa Kumiko K Saito Yoshiro Y Kikura-Hanajiri Ruri R Arakawa Noriaki N

Journal of proteome research 20250228 4

Diffuse alveolar damage (DAD) is a pathological hallmark of severe interstitial lung diseases, such as acute respiratory distress syndrome (ARDS), and is linked to poor prognosis. Previously, we identified 14-3-3σ/stratifin (SFN) as a serum biomarker candidate for diagnosing DAD. To clarify the time-dependent relationship between SFN expression and DAD, we here investigated pathological and molecular changes in serum, bronchoalveolar lavage fluid (BALF), and lung tissue in an oleic acid (OA)-ind ...[more]

PMID: 40021485

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