Dataset Information
Candidate disease progression biomarkers in AD
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ FT
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Hendrickson, RC
PROVIDER: MSV000079192 | MassIVE | Wed Jul 15 09:30:00 BST 2015
SECONDARY ACCESSION(S): PXD002546
REPOSITORIES: MassIVE
Publications
High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer's Disease in Human Cerebrospinal Fluid.
PloS one 20150813 8
Disease modifying treatments for Alzheimer's disease (AD) constitute a major goal in medicine. Current trends suggest that biomarkers reflective of AD neuropathology and modifiable by treatment would provide supportive evidence for disease modification. Nevertheless, a lack of quantitative tools to assess disease modifying treatment effects remains a major hurdle. Cerebrospinal fluid (CSF) biochemical markers such as total tau, p-tau and Ab42 are well established markers of AD; however, global q ...[more]
