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Comparison of lysine acetylation levels in wt and an acetate kinase mutant in Neisseria gonorrhoeae

ABSTRACT: Lysine acetylation levels were compared in wt and an acetate kinase (ackA) mutant in Neisseria gonorrhoeae. Acetylated peptides were enriched for using affinity enrichment and were compared using label-free MS-1 quantification. Over a hundred acetylated lysine sites were shown to be regulated. A number of these sites were found to be involved in bacterial metabolism and some were found in proteins known to or predicted to play a role in pathogenesis.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Neisseria Gonorrhoeae (ncbitaxon:485)

SUBMITTER: Bradford W Gibson

PROVIDER: MSV000079335 | MassIVE |

SECONDARY ACCESSION(S): PXD002994

REPOSITORIES: MassIVE

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