Proteomics

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Primary human microvascular endothelial cells metabolome response to an icMERS coronavirus

ABSTRACT: Metabolomics data from cell culture; Treated with wild-type MERS-CoV, MERS-CoV mutants and mockulum; 5 biological replicates; time points 0, 12, 24, 36 & 48 h

INSTRUMENT(S): GC MS

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626)

SUBMITTER: Yoshihiro Kawaoka, Ralph Baric, Katrina Waters, Richard Smith and Thomas Metz 

PROVIDER: MSV000080017 | MassIVE | Thu Aug 04 12:02:00 BST 2016

REPOSITORIES: MassIVE

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Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host response to infection generated from 45 individual experiments involving human viruses from the Orthomyxoviridae, Filoviridae, Flaviviridae, and Coronaviridae families. Analogous experimental designs were im  ...[more]

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