Proteomic maps of breast cancer subtypes
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: 
Tamar Geiger
PROVIDER: MSV000080757 | MassIVE | Wed Mar 29 07:14:00 BST 2017
SECONDARY ACCESSION(S): PXD002619
REPOSITORIES: MassIVE
Publications
Proteomic maps of breast cancer subtypes.
Tyanova Stefka S Albrechtsen Reidar R Kronqvist Pauliina P Cox Juergen J Mann Matthias M Geiger Tamar T
Nature communications 20160104
Systems-wide profiling of breast cancer has almost always entailed RNA and DNA analysis by microarray and sequencing techniques. Marked developments in proteomic technologies now enable very deep profiling of clinical samples, with high identification and quantification accuracy. We analysed 40 oestrogen receptor positive (luminal), Her2 positive and triple negative breast tumours and reached a quantitative depth of >10,000 proteins. These proteomic profiles identified functional differences bet ...[more]
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