Proteomics

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Online non-contiguous fractionating and concatenating device coupled to two dimensional reverse phase/reverse phase liquid chromatography system for efficient and comprehensive proteomic analyses


ABSTRACT: The goal of the project is development of an online two dimensional reverse phase/reverse phase liquid chromatography (2D-RP/RPLC) separation platform, employing an online non-contiguous fractionating and concatenating device (NCFC fractionator) in order to provide highly improve separation orthogonality of the two RPs, resulting in significant increase in peptide identification sensitivity compared with those of the conventional contiguous 2D-RP/RPLC method.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Sang-Won Lee  

PROVIDER: MSV000080846 | MassIVE | Fri Mar 31 22:09:00 BST 2017

SECONDARY ACCESSION(S): PXD004710

REPOSITORIES: MassIVE

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Publications

Fifteen-minute consultation: Practical use of continuous glucose monitoring.

Soni Astha A   Wright Neil N   Agwu Juliana Chizo JC   Drew Josephine J   Kershaw Melanie M   Moudiotis Christopher C   Regan Fiona F   Williams Eleri E   Timmis Alison A   Ng Sze May SM  

Archives of disease in childhood. Education and practice edition 20210507 3


Type 1 diabetes is a self-managed condition. Regular monitoring of blood glucose (BG) levels has been the cornerstone of diabetes management. Finger prick BG testing traditionally has been the standard method employed. More recently, rapid advancements in the development of continuous glucose monitoring devices have led to increased use of technology to help children and young people with diabetes manage their condition. These devices have the potential to improve diabetes control and reduce hyp  ...[more]

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