Proteomics

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Rbm17 complex identification from mouse brain


ABSTRACT: Here we characterized a splicesomal sub-complex including the proteins RBM17, U2SURP and CHERP, and found that these proteins physically interact and regulate reciprocal posttranslational stability; individually knocked down, they cause widely overlapping and consistent splicing and gene expression changes of transcripts enriched for RNA processing factors.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Huda Y. Zoghbi  

PROVIDER: MSV000081776 | MassIVE | Mon Dec 04 08:53:00 GMT 2017

SECONDARY ACCESSION(S): PXD008363

REPOSITORIES: MassIVE

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