Proteomics

Dataset Information

0

MaxLFQ label-free quantification algorithm benchmark datasets

ABSTRACT: We developed a set of algorithms for label-free quantification, termed MaxLFQ, embedded into MaxQuant. This contains two datasets to benchmark MaxLFQ: The proteome benchmark dataset consists of of HeLa and E. coli lysates mixed at defined ratios. The dynamic range benchmark dataset consists of UPS1/UPS2 standards (Sigma) spiked into E. coli lysates and quantified against each other.

INSTRUMENT(S): LTQ Orbitrap, Q Exactive

ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606)

SUBMITTER: None Listed 

PROVIDER: MSV000081831 | MassIVE | Tue Dec 19 14:33:00 GMT 2017

SECONDARY ACCESSION(S): PXD000279

REPOSITORIES: MassIVE

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

The biology of graft-versus-host disease: experimental systems instructing clinical practice.

Markey Kate A KA   MacDonald Kelli P A KP   Hill Geoffrey R GR  

Blood 20140609 3

The last 6 decades have seen major advances in the understanding of immunologic diseases, driven by preclinical animal models. Indeed, bone marrow transplantation (BMT) has its genesis in rodent models dating back to the 1950s. Allogeneic BMT and its major complication, graft-versus-host disease (GVHD), represent a paradigm for the translation of preclinical concepts into clinical practice. The appreciation that GVHD can be thought of as a stepwise escalation in immune activation characterized b  ...[more]