Dataset Information
Mining waste streams of food production for bioactive plant polysaccharides that affect the fitness and expressed activities of targeted human gut microbes
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Microbiota (ncbitaxon:13613) Mus Musculus (ncbitaxon:10090)
SUBMITTER: 
Richard J. Giannone Robert L. Hettich
PROVIDER: MSV000082287 | MassIVE | Wed Apr 18 15:03:00 BST 2018
SECONDARY ACCESSION(S): PXD009535
REPOSITORIES: MassIVE
Publications
Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans.
Cell 20190901 1
Development of microbiota-directed foods (MDFs) that selectively increase the abundance of beneficial human gut microbes, and their expressed functions, requires knowledge of both the bioactive components of MDFs and the mechanisms underlying microbe-microbe interactions. Here, gnotobiotic mice were colonized with a defined consortium of human-gut-derived bacterial strains and fed different combinations of 34 food-grade fibers added to a representative low-fiber diet consumed in the United State ...[more]
