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A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host- pathogen interactions

ABSTRACT: 1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435) 2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)

INSTRUMENT(S): TripleTOF 5600, Q Exactive

ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 (ncbitaxon:93061) Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Frank Schmidt

PROVIDER: MSV000082483 | MassIVE | Thu Jun 21 02:42:00 BST 2018

REPOSITORIES: MassIVE

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A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions.

Michalik Stephan S Depke Maren M Murr Annette A Gesell Salazar Manuela M Kusebauch Ulrike U Sun Zhi Z Meyer Tanja C TC Surmann Kristin K Pförtner Henrike H Hildebrandt Petra P Weiss Stefan S Palma Medina Laura Marcela LM Gutjahr Melanie M Hammer Elke E Becher Dörte D Pribyl Thomas T Hammerschmidt Sven S Deutsch Eric W EW Bader Samuel L SL Hecker Michael M Moritz Robert L RL Mäder Ulrike U Völker Uwe U Schmidt Frank F

Scientific reports 20170908 1

Data-independent acquisition mass spectrometry promises higher performance in terms of quantification and reproducibility compared to data-dependent acquisition mass spectrometry methods. To enable high-accuracy quantification of Staphylococcus aureus proteins, we have developed a global ion library for data-independent acquisition approaches employing high-resolution time of flight or Orbitrap instruments for this human pathogen. We applied this ion library resource to investigate the time-reso ...[more]

PMID: 28887440

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