Proteomics

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Centromere maintenance during DNA replication by retention of centromeric CENP-A coupled to removal of non-centromeric CENP-A


ABSTRACT: Mass spectrometry was used to determine the components which associate with CENP-ATAP during replication in late S phase, following affinity purification of CENP-A nucleosomes. CENP-ATAP was immunoprecipitated from the chromatin fraction of randomly cycling cells or late S synchronized cells. Mass spectrometry was performed on Velos Orbitrap.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Don W. Cleveland  

PROVIDER: MSV000083592 | MassIVE | Mon Mar 18 11:51:00 GMT 2019

SECONDARY ACCESSION(S): PXD013385

REPOSITORIES: MassIVE

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