Proteomics

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Missing proteins identified from the haploid cell lines: HAP1 and KBM-7

ABSTRACT: Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expressed only in a few cell types. In order to identify missing proteins, we focused on extensively unexplored cell lines(HAP1, KBM-7).

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Min-Sik Kim  

PROVIDER: MSV000083952 | MassIVE | Mon Jun 10 14:13:00 BST 2019

SECONDARY ACCESSION(S): PXD006614

REPOSITORIES: MassIVE

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Chromosome-centric Human Proteome Project aims at identifying and characterizing protein products encoded from all human protein-coding genes. As of early 2017, 19 837 protein-coding genes have been annotated in the neXtProt database including 2691 missing proteins that have never been identified by mass spectrometry. Missing proteins may be low abundant in many cell types or expressed only in a few cell types in human body such as sperms in testis. In this study, we performed expression proteom  ...[more]

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