Changes in the strength of protein-protein interactions portend oncogenic activity and generate actionable targets for cancer
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive (Thermo Scientific instrument model HF)
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: 
Thomas A. Neubert
PROVIDER: MSV000085459 | MassIVE | Fri May 22 13:30:00 BST 2020
REPOSITORIES: MassIVE
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This model is described in the article:
The molecular basis of the
interactions between synthetic retinoic acid analogues and the
retinoic acid receptors
Hesham Haffez, David R. Chisholm,
Roy Valentine, Ehmke Pohl, Christopher Redfern and Andrew
Whiting
MedChemComm
Abstract:
All-trans-retinoic acid (ATRA) and its synthetic analogues
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EC19 in cellular differentiation assays, and additionally, the
methods described herein can be further applied to the
understanding of the molecular basis for the selectivity of
different retinoids to RARα, β and
γ.
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