PGlyco3: Intact N- and O-glycopeptide search engine
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion ETD, Orbitrap Fusion
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Schizosaccharomyces Pombe (ncbitaxon:4896)
SUBMITTER: 
Wen-Feng Zeng
PROVIDER: MSV000086771 | MassIVE | Wed Jan 27 03:28:00 GMT 2021
REPOSITORIES: MassIVE
Publications
Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3.
Zeng Wen-Feng WF Cao Wei-Qian WQ Liu Ming-Qi MQ He Si-Min SM Yang Peng-Yuan PY
Nature methods 20211125 12
Great advances have been made in mass spectrometric data interpretation for intact glycopeptide analysis. However, accurate identification of intact glycopeptides and modified saccharide units at the site-specific level and with fast speed remains challenging. Here, we present a glycan-first glycopeptide search engine, pGlyco3, to comprehensively analyze intact N- and O-glycopeptides, including glycopeptides with modified saccharide units. A glycan ion-indexing algorithm developed for glycan-fir ...[more]
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