Proteomics

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High fiber diet mice methanol extracts


ABSTRACT: comparison between high fiber diet and ctrl mice methanol extraction, q exactive hf, 28 min method

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Sp. (ncbitaxon:10095)

SUBMITTER: Frank Schroeder  

PROVIDER: MSV000086890 | MassIVE | Tue Feb 16 14:24:00 GMT 2021

REPOSITORIES: MassIVE

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Publications


Dietary fibres can exert beneficial anti-inflammatory effects through microbially fermented short-chain fatty acid metabolites<sup>1,2</sup>, although the immunoregulatory roles of most fibre diets and their microbiota-derived metabolites remain poorly defined. Here, using microbial sequencing and untargeted metabolomics, we show that a diet of inulin fibre alters the composition of the mouse microbiota and the levels of microbiota-derived metabolites, notably bile acids. This metabo  ...[more]

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