Proteomics

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Global proteome profiling of Ulixertinib treated neuroblastoma cell


ABSTRACT: Ulixertinib has shown promising antitumor activity in a Phase 1 clinical trial for advanced solid tumors. In this study, we demonstrated that in NB cells, ulixertinib effectively suppressed ERK function of phosphorylating RSK and induced degradation of MYC that promotes NB development.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Sung Yun Jung  

PROVIDER: MSV000087511 | MassIVE | Tue May 25 08:15:00 BST 2021

REPOSITORIES: MassIVE

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