Proteomics

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Gluconeogenic/Glycolytic growth in P. putida KT2440 and C. testosteroni Kf1


ABSTRACT: Data comparing protein expression during gluconeogenic growth (on succinate) versus glycolytic growth (on gluconate) of P. putida KT2440 and C. testosteroni Kf1. Quantification by diDO-IPTL (Waldbauer et al. 2017 Analytical Chemistry).

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Pseudomonas Putida Kt2440 (ncbitaxon:160488) Comamonas Testosteroni Kf-1 (ncbitaxon:399795)

SUBMITTER: Jacob Waldbauer  

PROVIDER: MSV000087734 | MassIVE | Thu Jul 01 07:51:00 BST 2021

SECONDARY ACCESSION(S): PXD027036

REPOSITORIES: MassIVE

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Publications

Analogous Metabolic Decoupling in Pseudomonas putida and Comamonas testosteroni Implies Energetic Bypass to Facilitate Gluconeogenic Growth.

Wilkes Rebecca A RA   Waldbauer Jacob J   Aristilde Ludmilla L  

mBio 20211214 6


Gluconeogenic carbon metabolism is not well understood, especially within the context of flux partitioning between energy generation and biomass production, despite the importance of gluconeogenic carbon substrates in natural and engineered carbon processing. Here, using multiple omics approaches, we elucidate the metabolic mechanisms that facilitate gluconeogenic fast-growth phenotypes in Pseudomonas putida and Comamonas testosteroni, two <i>Proteobacteria</i> species with distinct metabolic ne  ...[more]

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