Proteomics

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Proteomics of high density lipoprotein subfractions in type 1 diabetes mellitus and controls


ABSTRACT: Toyoshima MTK. Proteomics and functionality of high-density lipoprotein subfractions and subclinical cardiovascular disease in type 1 diabetes mellitus. Faculdade de Medicina, Universidade de Sao Paulo 2021.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Marisa Passarelli  

PROVIDER: MSV000087986 | MassIVE | Fri Aug 13 11:47:00 BST 2021

SECONDARY ACCESSION(S): PXD027927

REPOSITORIES: MassIVE

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Proteomics of high-density lipoprotein subfractions and subclinical atherosclerosis in type 1 diabetes mellitus: a case-control study.

Toyoshima Marcos Tadashi K MTK   Santana Monique F M MFM   Silva Amanda R M ARM   Mello Gabriela B GB   Santos-Bezerra Daniele P DP   Goes Marisa F S MFS   Bosco Adriana A AA   Caramelli Bruno B   Ronsein Graziella E GE   Correa-Giannella Maria Lucia ML   Passarelli Marisa M  

Diabetology & metabolic syndrome 20230311 1


<h4>Background</h4>Subclinical atherosclerosis is frequently observed in type 1 diabetes (T1D) although the mechanisms and markers involved in the evolution to established cardiovascular disease are not well known. High-density lipoprotein cholesterol in T1D is normal or even high, and changes in its functionality and proteomics are considered. Our aim was to evaluate the proteomics of HDL subfractions in T1D and control subjects and its association with clinical variables, subclinical atheroscl  ...[more]

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