Proteomics

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Rewinding the molecular clock: chimpanzee, human, cow and pig tandem mass spectra for phylogenetic analysis


ABSTRACT: This repository contains the data underlying Figure 1 in our Perspective on the seminal 1960 PNAS paper "A Comparison of Animal Hemoglobins by Tryptic Peptide Pattern Analysis" by Emile Zuckerkandl, Richard T. Jones and Linus Pauling. These data and phylogenetic analysis are also available at https://osf.io/hm8dq/. The orbitrap data were graciously provided with permission from a collaboration with Dr. Michael G. Janech (College of Charleston) as part of the CoMPARe Program (Comparative Mammalian Proteome Aggregator Resource). Specifically, the cow samples were provided by Dr. Paola Boggiatto and Dr. Randy Sacco at the National Animal Disease Center, ARS, USDA, Ames, IA. The chimpanzee samples were provided by the Chattanooga Zoo, while the pig samples were from the Medical University of South Carolina (Charleston, SC). The human data were generated using digestions of NIST SRM 909c Frozen Human Serum. In addition to institutional permits and approval, data collection was performed under NIST ACUC MML-AR20-0001.

INSTRUMENT(S): Orbitrap Fusion Lumos, amaZon ETD

ORGANISM(S): Bos Taurus (ncbitaxon:9913) Pan Troglodytes (ncbitaxon:9598) Sus Scrofa (ncbitaxon:9823) Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Benjamin Neely   Magnus Palmblad  

PROVIDER: MSV000087993 | MassIVE | Tue Aug 17 07:59:00 BST 2021

REPOSITORIES: MassIVE

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