Chasing the elusive viscacha in Precolumbian textiles
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Camelidae (ncbitaxon:9835) Chinchillidae (ncbitaxon:10150)
SUBMITTER: 
Caroline Solazzo
PROVIDER: MSV000088203 | MassIVE | Thu Oct 07 19:26:00 BST 2021
REPOSITORIES: MassIVE
Similar Datasets
Project description:Paleoproteomics and dye analysis of Chancay textiles from Peru.
| MSV000095885 | MassIVE
Project description:The present study describes a novel xenograft-based biomarker discovery platform and proves its usefulness in the discovery of novel serum markers for prostate cancer (PCa). By immunizing immuno-competent mice with serum from nude mice bearing PCa xenografts, an antibody response against xenograft-derived antigens was elicited. By probing protein microarrays with serum from immunized mice, several PCa-derived antigens were identified, of which a subset was successfully retrieved in serum from mice bearing PCa xenografts and validated in human serum samples of PCa patients. In conclusion, this novel method allows for the identification of low abundant cancer-derived serum proteins, circumventing dynamic range and host-response issues in standard patient cohort proteomics comparisons.
2011-12-16 | GSE16220 | GEO
Project description:Bead-based proteomics MolPAGE study using sera from normoglycaemic twins
2008-11-02 | E-TABM-370 | biostudies-arrayexpress
Project description:The present study describes a novel xenograft-based biomarker discovery platform and proves its usefulness in the discovery of novel serum markers for prostate cancer (PCa). By immunizing immuno-competent mice with serum from nude mice bearing PCa xenografts, an antibody response against xenograft-derived antigens was elicited. By probing protein microarrays with serum from immunized mice, several PCa-derived antigens were identified, of which a subset was successfully retrieved in serum from mice bearing PCa xenografts and validated in human serum samples of PCa patients. In conclusion, this novel method allows for the identification of low abundant cancer-derived serum proteins, circumventing dynamic range and host-response issues in standard patient cohort proteomics comparisons. To perform a large-scale identification of antibodies generated against human PCa-derived proteins in the serum of immunized mice, sera from mice immunized with either depleted serum, full serum or both from PC346 and PC339-bearing mice as well as preimmune serum and serum from mice immunized with normal mouse serum were incubated onto ProtoArrays. These ProtoArrays contain approximately 8,000 partial and full-length human proteins, expressed as N-terminal glutathione S-transferase (GST) fusion proteins. To detect antibodies bound to spotted proteins, ProtoArrays were developed using a fluorescent labeled secondary antibody. Before being used for immunization, serum from xenografted mice was not treated (full) or depleted for most abundant proteins (depleted). Two arrays were hybridized with pre-immune serum and one array with serum from an immune competent mouse that was immunized with serum from a nude mouse. Six arrays were performed using serum from immune competent mice that were immunized with serum from xenograft-bearing nude mice.
2011-12-16 | E-GEOD-16220 | biostudies-arrayexpress
Project description:Protein-based or animal-based metal threads were largely used between the 10th and the 15th centuries, in European, Middle Eastern and Far Eastern textile productions for the decoration of textiles and cloths to make a display of wealth, power and status. A total of 91 samples were collected from a corpus of 66 textile fragments belonging to 54 catalogued objects. Proteomics analysis allowed to determine the origin of the animal substrates, which were found to be from cattle membranes (possibly from gastrointestinal organs or bladder) in membrane strips, while in leather strips (possibly made from the corium or grain skin layer of the animals), goat (exclusively in Spanish samples) and sheep (in Middle Eastern/Italian and Far Eastern samples) were identified. Other protein-based components that made the strips were identified and associated to the adhesive binders.
2023-07-06 | MSV000092355 | MassIVE
Project description:The ageing population has grown quickly in the last half century with increased longevity and declining birth rate. This presents challenges to health services and the wider society. This review paper considers different aspects (e.g., physical, mental, and social well-being) of healthy ageing and how health devices can help people to monitor health conditions, treat diseases and promote social interactions. Existing technologies for addressing non-physical (e.g., Alzheimer's, loneliness) and physical (e.g., stroke, bedsores, and fall) related challenges are presented together with the drivers and constraints of using e-textiles for these applications. E-textiles provide a platform that enables unobtrusive and ubiquitous deployment of sensors and actuators for healthy ageing applications. However, constraints remain on battery, integration, data accuracy, manufacturing, durability, ethics/privacy issues, and regulations. These challenges can only effectively be met by interdisciplinary teams sharing expertise and methods, and involving end users and other key stakeholders at an early stage in the research.
| S-EPMC6832571 | biostudies-literature
Project description:A novel photodiode-embedded yarn has been presented and characterized for the first time, offering new possibilities for applications including monitoring body vital signs (including heart rate, blood oxygen and skin temperature) and environmental conditions (light, humidity and ultraviolet radiation). To create an E-Textile integrated with electronic devices that is comfortable, conformal, aesthetically pleasing and washable, electronic components are best integrated within the structure of a textile fabric in yarn form. The device is first encapsulated within a protective clear resin micro-pod before being covered in a fibrous sheath. The resin micro-pod and covering fibres have a significant effect on the nature of light received by the photoactive region of the device. This work characterised the effects of both encapsulating photodiodes within resin micro-pods and covering the micro-pod with a fibrous sheath on the opto-electronic parameters. A theoretical model is presented to provide an estimate for these effects and validated experimentally using two photodiode types and a range of different resin micro-pods. This knowledge may have wider applications to other devices with small-scale opto-electronic components. Wash tests confirmed that the yarns could survive multiple machine wash and drying cycles without deterioration in performance.
| S-EPMC6212443 | biostudies-literature