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MS/MS spectra of Trypsin-digested m(SahA-OphA) containing one-three methyl groups

ABSTRACT: LC-MS/MS spectra (HCD) of Trypsin-digested m(SahA-OphA) containing one-three methyl groups Paper title: xxx (Figure S20ABC)

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Omphalotus Olearius (ncbitaxon:72120) Shewanella Sp. 10n.286.48.b5 (ncbitaxon:1880834)

SUBMITTER: Seokhee Kim

PROVIDER: MSV000088369 | MassIVE | Thu Nov 11 23:23:00 GMT 2021

REPOSITORIES: MassIVE

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Publications

Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria.

Cho Hyunjin H Lee Hyunbin H Hong Kyungtae K Chung Hannah H Song Inseok I Lee Jun-Seok JS Kim Seokhee S

Biochemistry 20220121 3

Backbone N-methylation is one of the prominent peptide modifications that can greatly enhance the pharmacological properties of a peptide. Naturally occurring backbone N-methylated peptides are produced via nonribosomal or ribosomal pathways, the latter of which was only recently identified in the borosin family of ribosomally synthesized and post-translationally modified peptides. Although previous bioinformatic analyses have revealed new putative genes for borosin biosynthesis, t ...[more]

PMID: 35061348

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