Exosomes from GBM established cell lines (U87, U373) and GBM primary CSC
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: 
FEDERICA FRATINI
PROVIDER: MSV000088671 | MassIVE | Tue Jan 11 05:54:00 GMT 2022
SECONDARY ACCESSION(S): PXD030894
REPOSITORIES: MassIVE
Publications
miRNome and Proteome Profiling of Small Extracellular Vesicles Secreted by Human Glioblastoma Cell Lines and Primary Cancer Stem Cells.
Cifola Ingrid I Fratini Federica F Cardinali Beatrice B Palmieri Valentina V Gatti Giuliana G Selmi Tommaso T Donzelli Sara S Sacconi Andrea A Cesarini Valeriana V Marei Hany E HE Papi Massimilano M Blandino Giovanni G Cenciarelli Carlo C Falcone Germana G D'Agnano Igea I
Biomedicines 20220804 8
Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. Despite available therapeutic interventions, it is very difficult to treat, and a cure is not yet available. The intra-tumoral GBM heterogeneity is a crucial factor contributing to poor clinical outcomes. GBM derives from a small heterogeneous population of cancer stem cells (CSCs). In cancer tissue, CSCs are concentrated within the so-called niches, where they progress from a slowly proliferating phase. CSCs, as most tu ...[more]
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