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Cancer genes disfavoring T cell immunity identified via integrated systems approach

ABSTRACT: A375 melanoma cells were transduced with Cas9 and non-targeting (NT) or BIRC2-targeting sgRNAs. Cells were cultured for 20 days post gene-editing and cell pellets were collected for analysis. Separately, A375 melanoma cells were treated with LCL161 for 16 hours and cell pellets were collected for analysis.

INSTRUMENT(S): Orbitrap Fusion ETD

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Nicholas Restifo

PROVIDER: MSV000089737 | MassIVE | Mon Jun 27 10:38:00 BST 2022

REPOSITORIES: MassIVE

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