Ontology highlight
ABSTRACT:
INSTRUMENT(S): QE+
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Weiss, Daniel J
PROVIDER: MSV000090771 | MassIVE | Tue Nov 22 11:52:00 GMT 2022
SECONDARY ACCESSION(S): PXD038289
REPOSITORIES: MassIVE
Hoffman Evan T ET Uhl Franziska E FE Asarian Loredana L Deng Bin B Becker Chloe C Uriarte Juan J JJ Downs Isaac I Young Brad B Weiss Daniel J DJ
Biomaterials 20221224
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), are characterized by regional extracellular matrix (ECM) remodeling which contributes to disease progression. Previous proteomic studies on whole decellularized lungs have provided detailed characterization on the impact of COPD and IPF on total lung ECM composition. However, such studies are unable to determine the differences in ECM composition between individual anatomical regi ...[more]