Late endosomes,lysosomes isolated from frozen autopsy human brains age matched controls, Niemann Pick type C and juvenile CLN3 disease.
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ABSTRACT: An immunopurification strategy was used to isolate intact LE, Lys from frozen human autopsy brain samples. LE, Lys isolated from BA9 samples of JNCL patients were compared with age matched unaffected controls and Niemann Pick Type C (NPC) disease patients. The protein content of LE, Lys was analyzed using shotgun proteomics.
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Catherine Marquer
PROVIDER: MSV000091428 | MassIVE | Tue Mar 07 14:21:00 GMT 2023
REPOSITORIES: MassIVE
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