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Identification of antioxidant metabolites from Five Plants of the Polynesian Pharmacopoeia and Cosmetopoeia for skin care

ABSTRACT: Oxidative stress contributes to impairment of skin health and aspects in the wound healing process for pathologies such as acne, psoriasis or skin cancer. Five Polynesian medicinal plants, among the most traditionally used for skin care (cosmetopoeia and pharmacopoeia) are studied herein for their antioxidant properties: Calophyllum inophyllum, Gardenia taitensis, Curcuma longa, Cordia subcordata and Ficus prolixa. For this purpose, plant extracts were submitted to in vitro bioassays related to antioxidant properties and their bioactive constituents were identified by metabolomic analytical approach. UHPLC-MS/MS analysis was performed leading to characterize 61 metabolites. Compounds annotated for F. prolixa and C. subcordata were reported for the first time in those indigenous trees. Antioxidant properties were evaluated by TPC, DPPH and FRAP assays. F. prolixa extract was the most active one within antioxidant properties similar to ascorbic acid and showed antioxidant intracellular activity on HaCaT model by AOP1 assay. On-Line-HPLC DPPH allowed the identification of phenolic bioactive compounds. These results highlight the potential of F. prolixa aerial roots as a source of antioxidant for skin care topical applications.

INSTRUMENT(S): impact II

ORGANISM(S): Cordia Subcordata (ncbitaxon:163078) Ficus Prolixa (ncbitaxon:182123) Gardenia Taitensis (ncbitaxon:83587) Calophyllum Inophyllum (ncbitaxon:158927) Curcuma Longa (ncbitaxon:136217)

SUBMITTER: CHAMBON Marion

PROVIDER: MSV000092788 | MassIVE | Wed Aug 30 04:44:00 BST 2023

REPOSITORIES: MassIVE

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