Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: David Greening
PROVIDER: MSV000092971 | MassIVE |
REPOSITORIES: MassIVE
Yang Michael C MC Chin Ian L IL Fang Haoyun H Drack Auriane A Nour Shirin S Choi Yu Suk YS O'Connor Andrea J AJ Greening David W DW Kalionis Bill B Heath Daniel E DE
Acta biomaterialia 20240822
Decellularised extracellular matrix (dECM) produced by mesenchymal stromal cells (MSCs) is a promising biomaterial for improving the ex vivo expansion of MSCs. The dECMs are often deposited on high modulus surfaces such as tissue culture plastic or glass, and subsequent differentiation assays often bias towards osteogenesis. We tested the hypothesis that dECM deposited on substrates of varying modulus will produce cell culture environments that are tailored to promote the proliferation and/or li ...[more]