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HDX-MS of murine urokinase plasminogen activator and variants

ABSTRACT: HDX-MS data revealing long-range allostery that affects the catalytic activity of the serine protease, murine urokinase plasminogen activator. The allostery is mediated by the disordered region connecting the N-terminal EGF and kringle domains to the protease domain.

INSTRUMENT(S): Synapt G2-S HDMS

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Elizabeth Komives

PROVIDER: MSV000094027 | MassIVE | Tue Feb 06 13:21:00 GMT 2024

SECONDARY ACCESSION(S): PXD049214

REPOSITORIES: MassIVE

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