Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: Omer Yilmaz John P. LaCava
PROVIDER: MSV000095444 | MassIVE | Fri Jul 26 01:41:00 BST 2024
SECONDARY ACCESSION(S): PXD054265
REPOSITORIES: MassIVE
Journal of proteins and proteomics 20240917 3
Data-Independent Acquisition (DIA) LC-MS/MS is an attractive partner for co-immunoprecipitation (co-IP) and affinity proteomics in general. Reducing the variability of quantitation by DIA could increase the statistical contrast for detecting specific interactors versus what has been achieved in Data-Dependent Acquisition (DDA). By interrogating affinity proteomes featuring both DDA and DIA experiments, we sought to evaluate the spectral libraries, the missingness of protein quantity tables, and ...[more]