Dataset Information

Molecular mechanisms of growth differences in large yellow croaker: Metabolomic and metagenomic analyses

ABSTRACT:

Gut microbiota can modulate nutrient metabolism, considerably affecting host growth and development. However, mechanisms by which gut microbiota regulate large yellow croaker (LYC; Larimichthys crocea) growth remain unclear. We assessed gut contents of fast-growing male (IWHM) and female (IWHF) LYCs and slow-growing male (IWLM) and female (IWLF) LYCs and subjected the data to metagenomic and metabolomic analyses. Gut microbiota composition significantly differed among LYCs with different growth rates: Vibrio abundance was considerably lower in IWHM LYCs (2.53%) than in IWLM LYCs (41.47%); Arthrobacter D abundance was the highest in IWHF LYCs (8.19%) but the lowest in IWLF LYCs (1.52%). Moreover, 124 and 483 differential metabolites were noted in IWHM-IWLM and IWHF-IWLF LYC pairs, respectively. Finally, we established a model for gut microbiota-metabolite relationship in LYCs to understand molecular mechanisms by which gut microbiota regulates nutrient metabolism. Our results highlight differences in gut microbiota between LYCs with high and low growth rates and provide comprehensive insights into molecular mechanisms underlying LYC growth regulation by gut microbiota.

INSTRUMENT(S): Liquid Chromatography MS - positive - hilic, Liquid Chromatography MS - negative - hilic

SUBMITTER: Huang Hao

PROVIDER: MTBLS10000 | MetaboLights | 2024-08-02

REPOSITORIES: MetaboLights

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			Action	DRS
	MTBLS10000	Other
	FILES	Other
	a_MTBLS10000_LC-MS_negative_hilic_metabolite_profiling.txt	Txt
	a_MTBLS10000_LC-MS_positive_hilic_metabolite_profiling.txt	Txt
	i_Investigation.txt	Txt

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Molecular mechanisms of growth differences in large yellow croaker: Metabolomic and metagenomic analyses

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