Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker
SUBMITTER: Maria Vinaixa
PROVIDER: MTBLS247 | MetaboLights | 2017-02-23
REPOSITORIES: MetaboLights
Action | DRS | |||
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MTBLS247 | Other | |||
FILES | Other | |||
a_MTBLS247_13C_EXD2_NMR_spectroscopy.txt | Txt | |||
a_MTBLS247_13C_PEPA_NMR_spectroscopy.txt | Txt | |||
a_MTBLS247_HSQC_EXD2_NMR_spectroscopy.txt | Txt |
Items per page: 1 - 5 of 15 |
Angewandte Chemie (International ed. in English) 20170221 13
A novel metabolomics approach for NMR-based stable isotope tracer studies called PEPA is presented, and its performance validated using human cancer cells. PEPA detects the position of carbon label in isotopically enriched metabolites and quantifies fractional enrichment by indirect determination of <sup>13</sup> C-satellite peaks using 1D-<sup>1</sup> H-NMR spectra. In comparison with <sup>13</sup> C-NMR, TOCSY and HSQC, PEPA improves sensitivity, accelerates the elucidation of <sup>13</sup> C ...[more]