Ontology highlight
ABSTRACT:
INSTRUMENT(S): Nuclear Magnetic Resonance (NMR) -
SUBMITTER: Christoph Trautwein
PROVIDER: MTBLS3873 | MetaboLights | 2022-09-07
REPOSITORIES: MetaboLights
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MTBLS3873 | Other | |||
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a_MTBLS3873_NMR___metabolite_profiling.txt | Txt | |||
files-all.json | Other | |||
i_Investigation.txt | Txt |
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JCI insight 20220208 3
The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present an unprecedented and valuable resource for tissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and tumor treatments in 101 tissue samples from 73 diffuse glioma pati ...[more]