Metabolomics

Dataset Information

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Metabonomic analysis of human and 12 kinds of livestock mature milk


ABSTRACT:

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites in 13 species of mammalian mature milk, which were grouped into 17 major metabolite classes with 1992 metabolites based on chemical classification. KEGG shows that 5 pathways in which differentially significant metabolites are actively involved are ABC transporters, Purine metabolism, Pyrimidine metabolism, Phosphotransferase system, Galactose metabolism. The study found that pig milk and goat milk are closer to human milk and contain more nutrients that are beneficial to human health, followed by camel milk and cow milk. In the context of dairy production, the development of goat milk is more likely to meet human needs and health.

INSTRUMENT(S): Liquid Chromatography MS - positive - hilic, Liquid Chromatography MS - negative - hilic

SUBMITTER: Yinggang Sun 

PROVIDER: MTBLS6777 | MetaboLights | 2023-08-21

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
MTBLS6777 Other
FILES Other
a_MTBLS6777_LC-MS_negative_hilic_metabolite_profiling.txt Txt
a_MTBLS6777_LC-MS_positive_hilic_metabolite_profiling.txt Txt
files-all.json Other
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Publications


Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites in 13 species of mammalian mature milk, which were grouped into 17 major metabolite classes with 1992 metabolites based on chemical classification. KEGG shows that 5 pathways in which differentially signi  ...[more]

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