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Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

ABSTRACT:

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selecting four specific time points. We collected samples of ovarian and uterine tissues from five female Jining Gray goats at each time point: after birth (D1), 2-month-old (M2), 4-month-old (M4) and 6-month-old (M6). By combining transcriptomic sequencing of 40 samples (including rRNA-depleted RNA-seq libraries with 3607.8 million reads and miRNA-seq libraries with 444.0 million reads) and metabolomics analysis, we investigated the transcriptomic mechanisms involved in reproductive regulation in the ovary and uterus during sexual maturation, as well as the changes in metabolites and their functional potential. Additionally, we analyzed blood hormone indices and uterine tissue sections to examine temporal changes. These datasets will provide a valuable reference for the reproductive regulation of the ovary and uterus, as well as the regulation of metabolites during sexual maturation in goats.

Ovarian data is reported in the current study MTBLS9794.

Uterine data is reported in MTBLS9795.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

SUBMITTER: wnag yanyan

PROVIDER: MTBLS9794 | MetaboLights | 2024-05-30

REPOSITORIES: MetaboLights

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			Action	DRS
	MTBLS9794	Other
	FILES	Other
	a_MTBLS9794_LC-MS_negative_reverse-phase_metabolite_profiling.txt	Txt
	a_MTBLS9794_LC-MS_positive_reverse-phase_metabolite_profiling.txt	Txt
	i_Investigation.txt	Txt

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Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

Project description:The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selecting four specific time points. We collected samples of ovarian and uterine tissues from five female Jining Gray goats at each time point: after birth (D1), 2-month-old (M2), 4-month-old (M4) and 6-month-old (M6). By combining transcriptomic sequencing of 40 samples (including rRNA-depleted RNA-seq libraries with 3607.8 million reads and miRNA-seq libraries with 444.0 million reads) and metabolomics analysis, we investigated the transcriptomic mechanisms involved in reproductive regulation in the ovary and uterus during sexual maturation, as well as the changes in metabolites and their functional potential. Additionally, we analyzed blood hormone indices and uterine tissue sections to examine temporal changes. These datasets will provide a valuable reference for the reproductive regulation of the ovary and uterus, as well as the regulation of metabolites during sexual maturation in goats. Uterine data is reported in the current study <a href='https://www.ebi.ac.uk/metabolights/MTBLS9795' rel='noopener noreferrer' target='_blank'>MTBLS9795</a>.Ovarian data is reported in <a href='https://www.ebi.ac.uk/metabolights/MTBLS9794' rel='noopener noreferrer' target='_blank'>MTBLS9794</a>.

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Transcriptomic data of Jining gray goat ovarian and uterine tissues during sexual maturation

Project description:Transcriptomic data of Jining gray goat ovarian and uterine tissues during sexual maturation

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Integrated analysis of miRNA and mRNA expression profiles in 2-, 6- and 12-month-old Small Tail Han Sheep testes to explore the regulation in testis development

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