Other,Multiomics

Dataset Information

272

Timecourse: Treatment of Arabidopsis cell suspension cultures with rotenone


ABSTRACT: A time-course treatment of Arabidopsis cell suspension culture with the mitochondrial Complex I inhibitor, rotenone, to reveal interactions between Complex I and primary metabolism.

OTHER RELATED OMICS DATASETS IN: E-MEXP-1797

INSTRUMENT(S): 1D-GC-EI-Q-MS

SUBMITTER: Adam J. Carroll  

PROVIDER: MEX2 | MetabolomeExpress | 2008-09-10

REPOSITORIES: MetabolomeExpress

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Publications

Complex I dysfunction redirects cellular and mitochondrial metabolism in Arabidopsis.

Garmier Marie M   Carroll Adam J AJ   Delannoy Etienne E   Vallet Corinne C   Day David A DA   Small Ian D ID   Millar A Harvey AH  

Plant physiology 20080910 3


Mitochondrial complex I is a major avenue for reduced NAD oxidation linked to oxidative phosphorylation in plants. However, the plant enzyme has structural and functional features that set it apart from its counterparts in other organisms, raising questions about the physiological significance of this complex in plants. We have developed an experimental model in which rotenone, a classic complex I inhibitor, has been applied to Arabidopsis (Arabidopsis thaliana) cell suspension cultures in order  ...[more]

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