Browse
Submit Data
Databases
API
Help

Dataset Information

198 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 1061

2 lines of pulmonary artery smooth muscle cells metabolic profile (122 vs 3633C central metabolic profile)

ABSTRACT: 2 lines of pulmonary artery smooth muscle cells which has been snap frozen during active growth phase

INSTRUMENT(S): QTOF

ORGANISM(S): Ovis Aries Sheep

TISSUE(S): Smooth Muscle

SUBMITTER: Maureen Kachman

PROVIDER: ST000180 | MetabolomicsWorkbench | Sat Jun 06 00:00:00 BST 2015

REPOSITORIES: MetabolomicsWorkbench

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	mwtab	Other

Items per page:

1 - 1 of 1

Similar Datasets

Pulmonary artery banded rat heart

Project description:Changes in juvenile rat heart with pulmonary artery banding

2022-05-20 | PXD027427 | Pride

Proteomics of CLIC4 overexpressing human pulmonary artery endothelial cells

Project description:To identify CLIC4 effectors by studying proteins expressiosn altered by CLIC4 overexpression in human pulmonary artery endothelial cells.

2018-10-16 | PXD008714 | Pride

Transcriptomic profile of CD31 and Griffonia simplicifolia isolectin B4 positive pulmonary artery endothelial cells isolated from a rat model of monocrotaline pulmonary arterial hypertension vs. control

Project description:Sprague Dawley rats were treated with monocrotaline 60 mg/kg by intraperitoneal injection or vehicle control on day 0. On day 23, animals were sacrificed and pulmonary artery endothelial cells (PAECs) were isolated for transcriptomic analysis.

2023-12-10 | GSE221097 | GEO

GNPS_2017 Mouse intermittent hypoxia (IH) - Aorta & pulmonary artery

Project description:2017 Mouse intermittent hypoxia (IH) - Aorta & pulmonary artery Contains LC/MS data for 10-week experiments involving mice raised in environments with normal oxygen, intermittent hypoxia (IH).

2019-02-25 | MSV000083483 | GNPS

human pulmonary artery (endothelial and smoorh muscle) cells : control vs ARSB-siRNA transfected

Project description:Transcriptional profiling of human pulmonary artery endothelial (HAPEC) and smooth muscle (PASM) cells comparing control untreated cells with cells transfected with ARSB-siRNA. Goal was to determine the effects of silenced of arylsufatase B on global gene expression in HAPEC and PASM cells.

2018-10-01 | GSE115268 | GEO

Transcriptional Profiles of Pulmonary Artery Endothelial Cells in Pulmonary Hypertension

Project description:Transcriptional Profiles of Pulmonary Artery Endothelial Cells in Pulmonary Hypertension

| PRJNA1017369 | ENA

CLIC4 interacting proteins - To identify proteins in human pulmonary artery endothelial cells that interact with CLIC4

Project description:To identify proteins in human pulmonary artery endothelial cells that interact with CLIC4

2018-10-16 | PXD008709 | Pride

Effects of BMPR2 Loss in Human Pulmonary Artery Endothelial Cells

Project description:Pulmonary arterial hypertension (PAH) is a fatal disease characterized by a proliferative endothelial cell phenotype, inflammation and pulmonary vascular remodeling. BMPR2 loss-of-function has been linked to pathologic plexiform lesions with obliteration of distal pulmonary arteries distal pulmonary arteries BMPR2 silencing inprimary human pulmonary artery ECs (HPAECs) recapitulate important aspects of cellular dysfunction and deregulated signaling associated with PAH. Primary HPAECs were transfected with gene-specific siRNA pools targeting BMPR2 or control siRNA followed PMA or control stimulation.

2015-12-04 | E-GEOD-70456 | biostudies-arrayexpress

Apelin/APJ targeted microRNAs in pulmonary artery endothelial cells

Project description:Evaluation of microRNAs that are downstream of apelin/APJ signaling in the pulmonary artery endothelial cells.

2012-12-04 | GSE42343 | GEO

Gene expression profiles based on Pulmonary Artery Pressures in Pulmonary Fibrosis

Project description:Pulmonary Hypertension (PH) is a frequent complication of Pulmonary Fibrosis (PF). PH can be seen in PF in the abscence of hypoxemia, irrespective of the degree of fibrosis. At the same time, a consistent number of patients with advanced PF never develop PH. The pathogenesis of PH secondary to PF remains unclear. PF patients are often referred to lung transplantation, but they present a higher incidence of pimary graft dysfunction than other diseases. The cause of this is unknown, and the relationship with PH remains unclear. We used microarray to identifiy the gene expression profiles in PF patients with and without PH Fresh frozen lung samples were obtained from the recipients organs of 116 PF patients undergoing lung transplantation. RNA was extracted and hybridized on Affymetrix microarrays. Pulmonary artery pressures were recorded intraoperatively with right heart catheters before starting lung transplantation. Patients were divided in different groups based on the mean pulmonary artery pressure. We compared the gene expression profiles in the group with severe PH (mPAP>40 mmHg, n=17) and in that without PH (mPAP<20 mmHg, n=22)) and obtained a gene signature, which was used for clusterying analysis. The clustering analysis based on the gene signature was then validated in an Intermediate PH group (mPAP 21-39 mmHg, n=45) and in a Validation Set (n=32).

2011-06-01 | E-GEOD-24988 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data