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ATF3 regulation of serine metabolism

ABSTRACT: ATF3 is a common stress sensor, and its expression can be induced by serine deprivation. The goal of this project is to determine whether ATF3 regulates serine biosynthesis. ATF3-wildtype and –knockout cells are cultured in complete or serine-free medium supplemented with 13C-6-glucose for 24 h for stable isotope tracing. The results show that ATF3 appears to promote serine biosynthesis.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Cultured Cells

SUBMITTER: Chunhong Yan

PROVIDER: ST001909 | MetabolomicsWorkbench | Wed Aug 11 00:00:00 BST 2021

REPOSITORIES: MetabolomicsWorkbench

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