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Perfluorinated compounds and high fat diet in relation to CVD-relevant metabolomic pathways in the SEARCH for Diabetes in Youth study

ABSTRACT: This project aims to evaluate the association between environmental exposure to perfluorinated alkyl substances (PFCs) and the development of risk factors for cardiometabolic disease in youth diagnosed with diabetes in the SEARCH Cohort Study. The longitudinal study of newly diagnosed cases of type 1 and type 2 diabetes examines serum metabolome changes at baseline and follow-up at approximately 5 years (all >3 years from baseline). Exposures to PFCs and biological effects characterized by serum metabolome changes will be associated with known cardiometabolic risk factors in youth diagnosed with diabetes.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Blood

DISEASE(S): Diabetes

SUBMITTER: ViLinh Tran

PROVIDER: ST001932 | MetabolomicsWorkbench | Wed Oct 06 00:00:00 BST 2021

REPOSITORIES: MetabolomicsWorkbench

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