Metabolomics

Dataset Information

0

Non-destructive characterization of Mesenchymal stem cells


ABSTRACT: Culture media from the growth of three different MSC cell lines (two bone marrow, one iPSC) were sampled daily for NMR metabolomics analysis. T cell proliferation and IDO assays were used as surrogates of anti-inflammatory function. Linear regression was used to assess the media metabolic changes over time, and partial least squares regression (PLSR) was then used to obtain predictive media markers (PMMs) based on variable importance in projection (VIP) scores. In addition, pathway analysis was performed to show the relations between media metabolites (MMs) and cell metabolites (CMs).

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Bone Marrow

SUBMITTER: Xunan Shen  

PROVIDER: ST001981 | MetabolomicsWorkbench | Thu Sep 16 00:00:00 BST 2021

REPOSITORIES: MetabolomicsWorkbench

Dataset's files

Source:
Action DRS
mwtab Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-09-29 | PXD035358 | JPOST Repository
2023-05-24 | MTBLS4854 | MetaboLights
2018-01-30 | GSE109755 | GEO
2018-01-13 | MSV000081933 | MassIVE
2023-12-31 | GSE222324 | GEO
2024-09-27 | GSE261001 | GEO
2022-11-29 | PXD032234 | Pride
2020-12-01 | GSE149216 | GEO
2009-06-22 | GSE15100 | GEO
2012-12-01 | E-GEOD-35901 | biostudies-arrayexpress