Metabolomics

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Data from plasma metabolome analysis of APP-KI and Wild type mice treated with B. breve MCC1274


ABSTRACT: Recently, we showed that administration of B. breve MCC1274 reduced amyloid-beta production, inhibited microglial activation, and suppressed inflammatory responses in the brains of APP knock-in (AppNL-G-F) mice. To elucidate the mechanism of action of this probiotic strain in an Alzheimer's disease-like model, we orally fed 3-month-old mice with B. breve MCC1274 or saline for 4 months and comprehensively investigated metabolites in plasma using CE-FTMS and LC-TOFMS.

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Blood

SUBMITTER: Kazuya Ohno  

PROVIDER: ST002153 | MetabolomicsWorkbench | Mon Apr 18 00:00:00 BST 2022

REPOSITORIES: MetabolomicsWorkbench

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