Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice (Aqueous)
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ABSTRACT: In the present study, we hypothesize that the creation of an iliac AVF would result in significant alterations to the limb muscle metabolome. Recently, our group developed a new murine model to address the pathophysiology of access-related hand dysfunction (ARHD) in mice, where AVF creation is performed in the iliac artery/vein. Because of the anatomical location of the AVF creation, this model produces clinically relevant changes in the mouse hindlimb including hemodynamic alterations, muscle weakness, and mitochondrial function impairment.
ORGANISM(S): Mouse Mus Musculus
TISSUE(S): Muscle
SUBMITTER: Terence Ryan
PROVIDER: ST002189 | MetabolomicsWorkbench | Thu Feb 17 00:00:00 GMT 2022
REPOSITORIES: MetabolomicsWorkbench
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