Multiplatform mass spectrometry-based analysis of Leishmania donovani infected macrophages at different time points after infection

ABSTRACT: The project aims to measure targeted and non-targeted metabolite data of intracellular extracts of uninfected and Leishmania-donovani infected macrophages at 0, 12, 36 and 72 hours post infection using a multiplatform mass spectrometry approach combining CE-TOF/MS (polar metabolites), LC-QTOF/MS (non-polar metabolites) and LC-QqQ/MS (polar metabolites) to characterize the dynamics of metabolic alterations ocurring in the human macrophage upon L. donovani infection.

ORGANISM(S): Human Homo Sapiens Homo Sapiens + Leishmania Donovani

TISSUE(S): Cultured Cells

DISEASE(S): Parasitic Infection

SUBMITTER: Miguel Fernández García  

PROVIDER: ST002285 | MetabolomicsWorkbench | Fri Jul 01 00:00:00 BST 2022

REPOSITORIES: MetabolomicsWorkbench