Metabolic impacts of metformin to seasonal influenza vaccination: a pilot study of drug interaction with the immune response
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ABSTRACT: We report here a double-blinded pilot study of seasonal influenza vaccination, where half of the participants received daily metformin administration. Global metabolomics was measured in the plasma samples at six timepoints. Metformin signatures were successfully identified in the metabolomics data. Statistically significant metabolite features were found both for the vaccination effect and for the drug-vaccine interactions.
ORGANISM(S): Human Homo Sapiens
TISSUE(S): Blood
DISEASE(S): Influenza
SUBMITTER: Amnah Siddiqa
PROVIDER: ST002432 | MetabolomicsWorkbench | Wed Jan 04 00:00:00 GMT 2023
REPOSITORIES: MetabolomicsWorkbench
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