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Mouse kidney metabolomics (Whole kidney)

ABSTRACT: Here, we reveal for the first time the misregulated metabolic pathways in TSC kidneys and their relevance to TSC-associated cytogenesis. To this end, we have analyzed the metabolic profile of the whole kidney as well as sorted proximal tubule cell (PTCs) extracts. The metabolomics data show that Tsc1 deletion in nephron progenitor cells changes the arginine biosynthesis pathway as well as a substantial number of metabolic pathways.

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Kidney

DISEASE(S): Chronic Kidney Disease

SUBMITTER: Iddo Ben-Dov

PROVIDER: ST002457 | MetabolomicsWorkbench | Mon Jan 30 00:00:00 GMT 2023

REPOSITORIES: MetabolomicsWorkbench

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