Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MiBC: the mouse intestinal Bacterial Collection

ABSTRACT: miBC: the mouse intestinal Bacterial Collection

PROVIDER: PRJEB11650 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Expanding the mouse intestinal bacterial collection (miBC)

Project description:Enriched cultured diversity of the mouse gut microbiota for custom-made synthetic communities

| PRJEB50452 | ENA

ELTE/DUTH Bacterial collection

Project description:ELTE/DUTH Bacterial collection, 16s rRNA gene sequences of 101 isolates

| PRJEB47054 | ENA

Kinome expression profiling of muscle invasive bladder cancer (MIBC) patients

Project description:Muscle invasive bladder cancer (MIBC) is one of the aggressive cancer with limited treatment options. Targeted gene expression profiling in normal and tumor samples from MIBC patients could aid in identification of potential therapeutic targets. Thus we used kinase specific panel to study their expression pattern and to identify targetable genes.

2020-04-20 | GSE130598 | GEO

The cultivable fraction of mouse gut

Project description:The mouse intestinal bacterial collection (miBC) represents a unique resource of cultivable bacteria isolates from mice that enables engineering of minimal gut consortia.

| PRJEB10572 | ENA

Mouse Intestinal HMGCR complex

Project description:Mice lacking 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Hmgcr) in intestinal villus and crypt epithelial cells were generated using a Villin-Cre transgene. Label free proteome profiling was measure for Wild type and KO mouse.

2021-06-08 | MSV000087589 | MassIVE

Molecular subtyping of “double negative” MIBC

Project description:Identifying patients that benefit from cisplatin-based adjuvant chemotherapy is a major issue in the management of muscle-invasive bladder cancer (MIBC). The purpose of this study is to correlate “luminal” and “basal” type protein expression with histological subtypes, to investigate the prognostic impact on survival after adjuvant chemotherapy and to define molecular subtypes of “double negative” patients (i.e. without expression of CK5/6 or GATA3).

2022-05-14 | GSE198607 | GEO

GATA4 regionalizes intestinal metabolism and commensal bacterial colonization to prevent immunopathology

Project description:Different regions of the gastrointestinal tract have distinct digestive and absorptive functions, which may be locally disrupted by infection or autoimmune disease. Yet, the mechanisms underlying intestinal regionalization and its dysregulation in disease are not well understood. Here, we used mouse models, transcriptomics, and immune profiling to show that regional epithelial expression of the transcription factor GATA4 prevented adherent bacterial colonization and inflammation in the proximal small intestine by regulating retinol metabolism and luminal IgA. Loss of epithelial GATA4 expression increased mortality in mice infected with Citrobacter rodentium which was dependent on commensal microbiota induced immunopathology. In active celiac patients with villous atrophy, low GATA4 expression was associated with metabolic alterations, mucosal Actinobacillus, and increased IL-17 immunity. This study reveals broad impacts of GATA4-regulated intestinal regionalization and highlights an elaborate interdependence of intestinal metabolism, immunity, and microbiota in homeostasis and disease.

2023-03-29 | GSE205743 | GEO

Molecular subtyping of “double negative” MIBC

Project description:Molecular subtyping of “double negative” MIBC

| PRJNA816119 | ENA

mouse intestinal microbiome

Project description:mouse intestinal microbiome Raw sequence reads

| PRJNA498866 | ENA

mouse intestinal microbiome

Project description:mouse intestinal microbiome Raw sequence reads

| PRJNA498867 | ENA